(1) Ibikoresho bibisi

Ibikoresho fatizo bya HPMC hollow capsule bikomoka cyane cyane kuri fibre yibihingwa bisanzwe (igiti cyinanasi), bitangiza ibidukikije, umutekano kandi wizewe.

Gelatin hollow capsule ikomoka ahanini kuri kolagen mu mpu zinyamaswa n'amagufwa.Mubikorwa byo kuvoma, hongewemo umubare munini wibigize imiti, byoroshye kumenyekanisha indwara zinka zasaze nindwara yamaguru n umunwa, nibindi.,.Mu myaka yashize, ibyabaye kuri "Poison Capsule" byagaragaje ibibazo byinshi bya capsules ya gelatine gakondo, nka "glue y'uruhu rw'ubururu" yashyizwe ahagaragara n'itangazamakuru, bigatuma chromium iri muri capsule irenga igipimo.

(2) Gukoreshwa & Imiti ihamye

HPMC ni inkomoko ya selile ifite ubudahangarwa bukomeye, ikoreshwa cyane, imiti ihamye, nta reaction ihuza imiti irimo aldehyde, kandi nta gutinda gusenyuka.

Lysine iguma muri gelatine, Iyo ukoresheje gelatine muri capsule, hazabaho gutinda gusenyuka.Ibiyobyabwenge byongera cyane bizaba bifite Maillard reaction hamwe na gelatine (Browning Reaction).Niba imiti irimo aldehyde, imiti igabanya isukari, cyangwa vitamine C, ntibikwiye rero gukoreshwa muri capsule ya gelatin.

(3) Ibirimo amazi

Amazi arimo capsule ya gelatin agera kuri 12.5% ​​kugeza 17.5%.Capsule ya gelatine irimo amazi menshi ikunda gukurura ubuhehere bwibiyobyabwenge cyangwa gufata amazi kubwuzuye, bigatuma capsule yoroshye cyangwa yoroheje, bigira ingaruka kumiti yuzuye ubwayo.

Amazi arimo capsule ya HPMC agera kuri 3% kugeza kuri 9%, atazitabira ibintu byuzuye, kandi ashobora kugumana ibintu byiza byumubiri nko gukomera mugihe yuzuza ibiyobyabwenge mubintu bitandukanye, Cyane cyane bikwiranye na hygroscopique no kuzuza ubushuhe ibiyobyabwenge byoroshye.

(4) Ibisigisigi byo kubungabunga

Ibintu nyamukuru bigize gelatin hollow capsule ni proteyine, byoroshye kororoka na bagiteri na mikorobe.Kurinda ibintu hamwe na bacteriostatike, birashobora gusigara muri capsule kugirango birinde mikorobe mugihe cyo kubyara.Niba umubare urenze urwego runaka, ibintu bya arsenic birashobora kurenga.Muri icyo gihe, capsules ya gelatin igomba guhindurwa na okiside ya Ethylene nyuma yumusaruro urangiye, kandi hakabaho chlorohydrin nyuma yo guhagarika sterile ya Ethylene.Mugihe ibisigazwa bya Chlorohydrin birabujijwe gukoreshwa.

HPMC hollow capsules ntabwo ikeneye kongeramo ibintu byose birinda ibintu mubikorwa byumusaruro, ntibikeneye guhindurwa, birashobora kuba byujuje ubuziranenge bwigihugu, kandi ni capsules nziza yicyatsi idafite ibisigisigi nibisigara.

(5) Ububiko

HPMC yuzuye capsules ifite uburyo bwo kubika neza, ku bushyuhe bwa 10 kugeza 30 ° C, hamwe nubushuhe buri hagati ya 35% na 65%, bitoroha cyangwa bikomera kandi bikavunika.HPMC hollow capsule ifite ifiriti ya ≤ 2% ku butumburuke bwa 35% naho capsule ihinduka ≤ 1% ku bushyuhe bwa 80 ° C;Kubika no gutwara muri zone zose zikirere ntakibazo.

Capsules ya Gelatin ikunda gufatirwa mugihe cy'ubushyuhe bwinshi;gukomera cyangwa gukonjesha mugihe cy'ubushyuhe buke, kandi bikagira ingaruka zikomeye kubushyuhe n'ubushuhe bwibidukikije.

(6) Ibidukikije

Gukuramo HPMC hollow capsule ibikoresho fatizo bikorwa no gukuramo umubiri.Yakuwe mu giti cya pinusi kandi ntabwo itanga umunuko uboze.Igabanya kandi ubwinshi bwamazi yakoreshejwe kandi ikagabanya kwanduza ibidukikije.Nta bintu byangiza byongeweho mugihe cyibikorwa kandi nta bihumanya ibidukikije bihari.

Gelatin hollow capsules ikozwe muruhu rwinyamaswa namagufwa nkibikoresho fatizo, bigakorwa muburyo bwa shimi kandi bigahinduka.Inzira yongeramo ibintu byinshi bigize imiti, itanga impumuro nini mugihe cyumusaruro, kandi ikoresha amazi menshi.Gutanga umwanda ukomeye;Nanone imyanda ya gelatine itunganyirizwa ni mike, kandi n’umwanda mwinshi uturuka mu gihe cyo kujugunya imyanda.

(7) Gutandukanya guhuza umwuka wo hanze

Ibikoresho fatizo bya HPMC hollow capsules byerekana ko ishobora gutandukanya neza ibiri hanze yisi kandi ikirinda ingaruka mbi hamwe numwuka, kandi ubuzima bwayo bumara amezi 24.

Gelatin capsule ifite igihe cyiza cyamezi 18, mugihe hari nigihe cyo kubika mbere yo kuyikoresha ituma capsule igira igihe gito cyo kubaho, ibyo bikaba bigira ingaruka mubuzima bwibi biyobyabwenge.

(8) Kubuza gukura kwa bagiteri

Ibikoresho nyamukuru bya HPMC hollow capsules ni fibre yibihingwa, ntabwo ikwirakwiza bagiteri gusa, ahubwo inabuza gukura kwa bagiteri.Ubushakashatsi bwerekanye ko capsules ya HPMC ishobora kubikwa mu bidukikije muri rusange igihe kirekire, kandi umubare w’ibinyabuzima ushobora kubikwa munsi y’urwego rusanzwe.

Ibikoresho nyamukuru bya gelatin hollow capsule ni kolagen, naho kolagen ni umuco wa bagiteri, ifasha bagiteri kugwira.Niba kuvura bidakwiye, umubare wa bagiteri uzarenza urugero kandi uzagwira.

Iherezo.